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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 914 - 19th December Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
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44 year-old male with upper back biopsy.
Clinical impression: mass.

Case posted by Dr. Hafeez Diwan.


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Guest Romualdo

Posted

Sparse bland small uniform spindle cells, brightly eosinophilic ropey collagen bundles, abundant myxoid matrix and rare mature adipocytes: myxoid variant of spindle cell lipoma in a typical location.

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Dr. Mona Abdel-Halim

Posted

I think these r ropey collagen in a myxoid to hyalinized stroma with sparse spindle cells and few adipocytes. I think this is spindle cell lipoma. In elastofibroma, one sees the thickened beaded elastic fibers in a back ground of a mixture of collagen and adipose tissue. Will love to know the correct answer.

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Robledo F. Rocha

Posted

[font="Arial, sans-serif"][size="4"]At first glance, elastofibroma, but I'm not satisfied that those swollen fibers shown in the pictures above are equivalent to the fungal hyphae-like elastic fibers fragmented into petaloid globules distinctively observed in elastofibroma. They might rather be wavy ropey collagen bundles of a myxoid neurofibroma.[/size][/font]

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Guest Jim Davie MD

Posted

[quote name='Romualdo' timestamp='1387451494']
Sparse bland small uniform spindle cells, brightly eosinophilic ropey collagen bundles, abundant myxoid matrix and rare mature adipocytes: myxoid variant of spindle cell lipoma in a typical location.
[/quote]

Agree completely with Romualdo and Mona. Myxoid SCL occasionally shows sparse or absent adipocytes.

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Guest Romualdo

Posted

Dr. Hafeez, may we see the microphotographs of the elastin stains?

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