Jump to content
In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 830 - 22nd August Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
   (0 reviews)

7-year-old female, one and a half years post bone marrow transplant for Blackfan Diamond anemia with hyperpigmented plaques with atrophy. The lesion biopsied is from the thigh.

Case posted by Dr. Hafeez Diwan.


  Report Record

User Feedback


Guest Romualdo

Posted

[font=arial,helvetica,sans-serif][b]Sclerodermatous chronic graft versus host disease.[/b][/font]

Share this comment


Link to comment
share_externally

Arti Bakshi

Posted

Dermal scarring, loss of adnexae, pigment incontinence, no active interface change.
c/w late stage of chronic GVHD (sclerodermoid)

Share this comment


Link to comment
share_externally

Guest Amira Tawdy

Posted

agree with chronic graft versus host disease

Share this comment


Link to comment
share_externally

Robledo F. Rocha

Posted

Sclerodermoid chronic graft-versus-host disease.

Share this comment


Link to comment
share_externally

Chronic GVHD - sclerodermoid stage. There´s some interface dermatitis which is also an element of lichenoid stage.

Share this comment


Link to comment
share_externally

Guest Rodrigo Restrepo

Posted

Chronic graft versus host disease

Share this comment


Link to comment
share_externally

Guest Jim Davie MD

Posted

Given history, a chronic GVHD (sclerodermoid/morpheaform variant) is reasonable.
There are sparse necrotic keratinocytes at the junction with sparse junctional lymphocytes, post-inflammatory hyperpigmentation, relatively normal epidermal architecture, and papillary/reticular dermal sclerosis with encased adnexa (arrector pilus).

Share this comment


Link to comment
share_externally

Guest Tiberiu Tebeica

Posted

Chronic GVHD, sclerodermoid phase. Interestingly, pediatric cases of sclerodermoid GVHD are rare!

Share this comment


Link to comment
share_externally



Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.

Guest
Add a comment...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

Loading...

×
×
  • Create New...