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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 666 - 2 Jan Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
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Female with blisters around her mouth and on her limbs.
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Go to records January 2013

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Guest Dr Engin Sezer

Guest Dr Engin Sezer

Posted

Stevens-Johnson's syndrome, confluent apoptotic keratinocytes as a clue for this clinicopathological entity.

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Arif Usmani

Arif Usmani 17

Posted

Erythema Multiforme

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Dr. Mona Abdel-Halim

Dr. Mona Abdel-Halim 508

Posted

EM spectrum

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Guest Hazem Hamed

Guest Hazem Hamed

Posted

I would also add TEN and grade 4 GVHD to the DD. Clinicopathological correlation is required.

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Azza Esmat

Azza Esmat 0

Posted

Stevens-Johnson's/TEN > EM due to confluent necrosis. also agree there may be some satellite cell necrosis? (GVHD)

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Dr. Phillip McKee

Dr. Phillip McKee 130

Posted

I agree that clinical information is required. The patient developed full blown TEN. I have forgotten what drug was involved. The histology would also be consistent with TEN-like GVHD. The involvement of the limbs would suggest that the patient was going on to TEN rather than SJ syndrome. EM is also in the differential diagnosis.

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