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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 677 - 17 Jan Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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79 years-old male with chronic wound on left medial lower leg. A biopsy was performed to rule out skin cancer.

Case posted by Dr. Hafeez Diwan
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Guest Hazem Hamed

Guest Hazem Hamed

Posted

Basal cell carcinoma with neuroendocrine differentiation. Clefting and mucin are seen in 2nd image and a hint of peripheral pallisading in 3rd image.

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Guest
There is connection to the epidermis, mucinous stroma, clefting, vague palisading, moderate quantity of oesinophilic cytoplasm and visible nucleoli. Additionally, the clinical course seems to be indolent ("chronic wound"). All this points towards basal cell carcinoma with neuroendocrine differentiation (and away from Merkel).

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Azza Esmat
Agree BCC with neuroendocrine differentiation

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Dr. Mona Abdel-Halim

Dr. Mona Abdel-Halim 508

Posted

Yes BCC with neuroendocrine differentiation.

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Arif Usmani

Arif Usmani 17

Posted

Agree.

Basal cell carcinoma with neuroendocrine differentiation arising in a scar: A case report
Manuela Krokowski MD[sup]1[/sup], Josef Hoch MD[sup]2[/sup], Alfred C Feller MD[sup]1[/sup], Heinz-Wolfram Bernd MD[sup]1[/sup], Christoph Thorns MD[sup]1[/sup], Stefan Krueger MD[sup]3 [/sup]Dermatology Online Journal 15 (10): 4

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Dr. Hafeez Diwan

Dr. Hafeez Diwan 125

Posted

Yes. This is a basal cell carcinoma with neuroendocrine differentiation.

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