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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 679 - 21 Jan Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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37 years old female, hair loss.


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Robledo F. Rocha

Posted

Lymphocytic scarring alopecia due to discoid lupus erythematosus, typically occurring to a middle aged woman. Clues are pronounced epidermal atrophy, basement membrane thickening and pigmentary incontinence.

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Guest Dr. Francisco Vílchez

Posted

Agree, DLE

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Guest Jim Davie MD

Posted

[b]Favor scarring alopecia, DLE type.[/b]
Loss of sebaceous glands, superficial and deep reticular dermal perivascular inflammation, compact hyperkeratosis, hypergranulosis, and features RR mentioned. (There is preservation of follicles but these are tangentially oriented and likely represent proper punch at a lesion edge). Patient age is representative. Horizontal sections are likely going to be non-contributory given the above features.

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Robledo F. Rocha

Posted

[quote name='Jim Davie MD' timestamp='1358778934']
[b]Favor scarring alopecia, DLE type.[/b]
[color=#1C2837][font=arial, verdana, tahoma, sans-serif][size=4]Loss of sebaceous glands, superficial and deep reticular dermal perivascular inflammation, compact hyperkeratosis, hypergranulosis, and features RR mentioned. (There is preservation of follicles but these are tangentially oriented and likely represent proper punch at a lesion edge). Patient age is representative. Horizontal sections are likely going to be non-contributory given the above features.[/size][/font][/color]
[/quote]
Agree that transverse (horizontal) sections wouldn´t be helpful. Here this grossing technique would give rise to a diagnosis of pseudopelade of Brocq, an inespecific form of end-stage scarring alopecia.

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Dr. Phillip McKee

Posted

Hi everyone. It is nice to be back after a vacation in France. Obviously you are all correct. This is classical scarring alopecia due to DLE. It is nice to see so many people posting today.

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