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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 812 - 29th July Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
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The patient is a 13 year-old white boy with a two year history of a scaly eruption. A punch biopsy is taken from the left side of the neck.

Case posted by Dr Mark Hurt.


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Guest Engin Sezer

Posted

FAD consistent with Darier's disease

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Guest Maria George

Posted

[color=#1C2837][font=arial, verdana, tahoma, sans-serif][size=4]Agree with Sezer, Darier's disease.[/size][/font][/color]

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Guest Dr. Francisco Vílchez

Posted

Agree, Darier.

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Robledo F. Rocha

Posted

Darier’s disease, typically featuring acantholytic suprabasal cleft overlayed by dyskeratotic keratinocytes.

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Darier´s disease. It could be also Grover disease.

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Guest Romualdo

Posted

Darier's disease. In Grover's disease the clinical context is different, the inflammatory infiltrate heavier an the acantholytic dyskeratotic foci much more limited.

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Mark A. Hurt MD

Posted

Yes, this is Darier-White disease. The clinical differential was Hailey-Hailey, Darier's disease, and ichthyosis.

Congratulations to everyone.

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Romualdo is right. I had not seen the clinical history, but the histological aspects can be very similar.

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