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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 778 - 11th May Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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47 years-old female - Punch biopsy left labia H/o soreness and fissuring labia.

Thank you to Dr. Leena Joseph for providing this case.


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Guest Dr. Francisco Vílchez

Posted

Lichen sclerosus

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Robledo F. Rocha

Posted

Epidermis shows blunting of the rete pegs and hyperkeratosis. In the dermis one can find a zone of homogeneous hyalinized edema of the papillary dermis and an underlying band of lymphocytic infiltrate. A follicular plugging can also be seen.
I go with lichen sclerosus et atrophicus, formerly known as kraurosis vulvae.

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Sasi Attili

Posted

Classical LS

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Dr. Mona Abdel-Halim

Posted

Lichen sclerosus et atrophicus... Classic

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Guest Dr Engin Sezer

Posted

Agree LS

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Guest Dr. Pablo Ortega

Posted

Lichen sclerosus atrophicys!

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Guest Maria George

Posted

Lichen sclerosus is the best term since it can be atrophicus and can be hypertrophicus.In long standing lesion , malignany (SCC) can develop.

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Guest Amira Tawdy

Posted

agree lichen sclerosis

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Robledo F. Rocha

Posted

[quote name='Maria George' timestamp='1370957040']
Lichen sclerosus is the best term since it can be atrophicus and can be hypertrophicus.
[/quote]
Give a name to a disease is really an ungrateful task since it’s hard to sum up all the clinical, microscopic and other important medical features in a few words. And the task is even harder if you take in mind the different presentations of a disease according to the site and to the developing stage.
Lichen sclerosus et atrophicus is not exception to this rule. Early genital lesions are not sclerotic at all, and most of the fully developed extragenital plaques are only, if so, slightly sclerotic.
I’m aware of the preference for the shorter term "lichen sclerosus" by the majority of today’s authors.

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Iskander H. Chaudhry

Posted

Well done everyone, it is lichen sclerosus et atrophicus.

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Guest Maria George

Posted

Thank you Rocha.Also small correction in the stem of the question above labia minora is [color=#444444][font=arial, sans-serif][size=1][b][right]plural[/right][/b][/size][/font][/color][color=#444444][font=arial, sans-serif][size=1][right] form of [/right][/size][/font][/color][color=#444444][font=arial, sans-serif][size=1][b][right]labia[/right][/b][/size][/font][/color][color=#444444][font=arial, sans-serif][size=1][right] minus and [/right][/size][/font][/color][color=#444444][font=arial, sans-serif][size=1][b][right]labia[/right][/b][/size][/font][/color][color=#444444][font=arial, sans-serif][size=1][right] majora is the [/right][/size][/font][/color][color=#444444][font=arial, sans-serif][size=1][b][right]plural[/right][/b][/size][/font][/color][color=#444444][font=arial, sans-serif][size=1][right] form of [/right][/size][/font][/color][color=#444444][font=arial, sans-serif][size=1][b][right]labia[/right][/b][/size][/font][/color][color=#444444][font=arial, sans-serif][size=1][right] majus.[/right][/size][/font][/color]

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Robledo F. Rocha

Posted

Yes, Dra. Maria George, you're a great observer! However, your observation requires a small touch-up.
In latin, the plural form is “labia” and the singular form is “labium”. So, today’s history case should be corrected to “left labium” and “fissuring labium”.

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