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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 721 - 21 Mar Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
   (0 reviews)
67 years-old female with a left mid back soft tissue mass.

Case posted by Dr. Hafeez Diwan
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Go to records March 2013

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Guest Dr Engin Sezer

Guest Dr Engin Sezer

Posted

Myxoid malignant fibrous histiocytoma vs. myxoid melanoma (suggesting S100, HMB34)

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Guest Dr Engin Sezer

Guest Dr Engin Sezer

Posted

Sorry HMB45

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Guest Maria george

Guest Maria george

Posted

high grade myxofibrosarcoma

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Eman El-Nabarawy

Eman El-Nabarawy 69

Posted

Myxofibrosarcoma.

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Guest Bansal_

Guest Bansal_

Posted

DD: Undifferentiated pleomorphic sarcoma, anaplastic carcinoma, melanoma. Requires immunohistochemistry.

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Guest Jim Davie MD

Guest Jim Davie MD

Posted

High grade tumor with mixed spindled, epithelioid and dendritic cytology, prominent nucleoli but absence of bizarre pleomorphism, rare multinucleation, cytoplasmic vacuolation. Mass necrosis. Curvilinear, sparse vasculature and tumor infiltrating neutrophils. Variably mucinous stroma without mast cells.
- Grade II myxofibrosarcoma - most common tumor, good match for histology, location/age.
- Myxoid Melanoma (greatly doubt, but rule out)
- Myxoid liposarcoma (greatly doubt, but rule out)
Stains : S100, SOX10, CD34, SMA, Desmin

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Dr. Hafeez Diwan

Dr. Hafeez Diwan 125

Posted

Inflammatory malignant fibrous histiocytoma.

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Guest cerub

Guest cerub

Posted

In the mid back topography I think too in metastatic sarcomatous renal cell carcinoma!

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