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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 889 - 14th November Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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66-year-old with large lesion on his left chin. A month later a chest lesion was biopsied. The patient has a history of urothelial carcinoma (2 years prior to these biopsies).

Case posted by Dr. Hafeez Diwan.


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Guest Dr.Yüksel Okumuş

Posted

Metastatic urothelial carcinoma with squamous differantiation
DDX. Sebaceous carcinoma of extraocular sites

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Metastatic carcinoma, consistent with metastatic urothelial carcinoma, with foci of keratinous, clear cell and lipoid morphology.

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Robledo F. Rocha

Posted

At first glance I thought it was sebaceous carcinoma. But after read the case history, I think it is metastatic urothelial carcinoma.

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Dr. Mona Abdel-Halim

Posted

Definitely this is a metastatic carcinoma. I have not seen urothelial metastases before, but I checked images and found these images presented here fitting with metastatic urothelial carcinoma... Lovely yet scary as with all cancerous conditions....

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Guest Juan Carlos Garcés, Ecuador

Posted

[b][s][s]Agree with metastasic urthelial carcinoma[/s][/s][/b]

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Guest Romualdo

Posted

It may well be a metastatic urothelial carcinoma with squamous diferentiaton but I am not sure primary squamous carcinoma can be excluded without immunohistochemistry or finding focal in situ squamous carcinoma after reviewing the histologic sections.

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Dr. Hafeez Diwan

Posted

My apologies for the delayed comment! I was occupied with back to back meetings. But yes, this metastatic urothelial carcinoma, with extensive squamous differentiation. The primary looked just like this in areas (with other areas looking like garden variety transitional carcinoma).

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