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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 859 - 2nd October Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
   (0 reviews)
74 year-old male with a rash on his abdomen.

Case posted by Dr. Hafeez Diwan.
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Go to records October 2013

User Feedback


Guest Romualdo

Guest Romualdo

Posted

Despite the somewhat extensive suprabasal acantholysis I think Grover's disease is the first possibility.

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Guest Marwa Fawzy

Guest Marwa Fawzy

Posted

Superficial pemphigus .Need IF to confirm

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Guest Saleem Taibjee

Guest Saleem Taibjee

Posted

Differential diagnosis is Grovers vs Pemphigus foliaceous. Clinical correlation and IMF required.

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Sasi Attili

Sasi Attili 85

Posted

My initial impression was pemphigus (foliaceous, as the acantholysis appears superficial). The acantholysis is a bit too extensive for grovers, but CPC/ DIF required.

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Guest Giovanni Falconieri

Guest Giovanni Falconieri

Posted

Favor Grover, yet agree with the differential above

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Dr. Mona Abdel-Halim

Dr. Mona Abdel-Halim 508

Posted

Pemphigus, combined features of superficial and vulgaris types

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Guest Jim Davie MD

Guest Jim Davie MD

Posted

I lean towards Grover disease (pemphigus foliaceous / Darier variant).

Clinical data would be important: papular or papulovescicular vs plaque/patch, for helping differentiate Grover disease vs. a pemphigus variant. We are assuming this is a novel eruption. Agree with the above differentials in this regard, with DIF if clinically/histologically equivocal.

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Robledo F. Rocha

Robledo F. Rocha 336

Posted

I found more than one pattern of acantholysis, what make me favor Grover's disease. Lesions reaching a size that is larger than only a few rete ridges might crop up as well. In addition, abdominal region is a typical site for Grover's disease.

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Dr. Hafeez Diwan

Dr. Hafeez Diwan 125

Posted

Grover's disease. This is what the clinical impression was as well.

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