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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 872 - 22nd October Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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The patient is a five day old baby with a shave biopsy from the left thigh.

Case posted by Dr. Mark Hurt.


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Guest Saleem Taibjee

Posted

myofibroma - biphasic pattern is supportive. The infant would need a work-up to assess for multiple lesions including imaging.

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Sasi Attili

Posted

[color=#1C2837][font=arial, verdana, tahoma, sans-serif][size=4]infantile myofibromatosis/ myofibroma. Nice case....[/size][/font][/color]

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Robledo F. Rocha

Posted

[size=5][color=#000000][font=Palatino Linotype, serif]Solitary myofibroma displaying beautiful intravascular myofibroblastic clusters and foci of calcification. Increased expression of Ki-67 is expect in a few-days-aged infant.[/font][/color]
[font=Palatino Linotype, serif][color=#000000]As pointed out by Dr. Taibjee, it would be prudent if an in-depth investigation were carried out in order to look for [/color][color=#000000]multiple lesions [/color][color=#000000]involv[/color][color=#000000]ing[/color][color=#000000] superficial soft tissues, [/color][color=#000000]bones,[/color] [color=#000000]and[/color] [color=#000000]visceral organs, once solitary lesions are not common away from head and neck.[/color][/font][/size]

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Robledo F. Rocha

Posted

[quote name='Mark A. Hurt MD' timestamp='1382468747']
I was overly concerned with the massive necrosis in the lesion, as it is rarely shown or discussed.
[/quote]
Very interesting, Dr. Hurt. Although there's no supportive data from the literature, I got a sense that the more frequent the intravascular growth, the more extensive the necrosis. Perhaps this observation may spark interest among researchers.
Thanks for share this nice case.

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