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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 876 - 28th October Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
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The patient is a 44-year-old white man with excisions taken from A - the left temple by the forehead.

Case posted by Dr. Mark Hurt.


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Guest Maria George

Posted

[color=#444444][font=arial, sans-serif][size=1][b][right]Epidermodysplasia verruciformis[/right][/b][/size][/font][/color][color=#444444][font=arial, sans-serif][size=1][right] (EV).[/right][/size][/font][/color]

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Robledo F. Rocha

Posted

A plane wart-like lesion on the head that shows thickened epidermis with striking swollen keratinocytes only in the upper layers is indicative of epidermodysplasia verruciformis.

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Guest Jim Davie MD

Posted

[color=#1C2837][font=arial, verdana, tahoma, sans-serif][size=4]Epidermodysplasia verruciformis. Atypical enlarged keratinocytes with light blue cytoplasm, arranged as wedge-shaped or columnar aggregates in the stratum spinosum.[/size][/font][/color]

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Mark A. Hurt MD

Posted

My diagnosis:

[b]-- VERRUCA PLANA WITH[/b]
[b]EPIDERMODYSPLASIA VERRUCIFORMIS LIKE CHANGES[/b]
[indent=1][b]COMMENT: [/b] These kinds of findings have been identified as focal lesions in what has been termed "EV acanthoma". Further correlation is suggested, as some patients can have lesions like this in a disseminated pattern.[/indent]

[center]Reference:[/center]

[indent=1]Ko CJ, Iftner T, Barr RJ, Binder SW. Changes of epidermodysplasia verruciformis in benign skin lesions: the EV acanthoma. J Cutan Pathol. 2007 Jan;34(1):44-8. PubMed PMID: 17214854.[/indent]

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Guest Jim Davie MD

Posted

EDV changes (clusters of large keratinocytes with voluminous blue cytoplasm, and atypical keratohyaline granules) are seen as incidental findings in a wide variety of lesions such as SK, verruca, etc.

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