Case Number : Case 850 - 19th September Posted By: Guest

Aopcrine cystadenoma

The cyst wall is lined by pseudostratified columnar epihelium. I think this is median raphe cyst.

favour median raphe cyst too.

site does suggest a median raphe cyst

[font="Palatino Linotype, serif"][size="4"]This cystic lesion with predominantly stratified epithelial lining, I presumed located on the ventral surface of the penis, is median raphe cyst. A bilayered epithelial lining even might be construed as hidrocystoma [url="http://archderm.jamanetwork.com/article.aspx?articleid=540492"]if this entity really occurs on penis as something other than median raphe cyst[/url].[/size][/font]

Median raphe cyst.

These may have a ciliated epithelial lining (which I can't see directly in the images above, but suspect may be present, given presence of the dark eosinophilic staining of the apical surfaces, suggestive of terminal bars associated with ciliated epithelium. Cilia have been reported in MRCs:
[url="http://www.medicaljournals.se/acta/content/?doi=10.2340/00015555-0286&html=1"]Median Raphe Cyst with Ciliated Cells of the Penis[/url] [the [url="http://www.medicaljournals.se/acta/content/download.php?doi=10.2340/00015555-0286"]PDF link[/url] version has better-quality images ]([i]Arch Dermatol. [/i][color=#333333][font=Helvetica, Arial, Verdana, sans-serif][size=3]1979;115(9):1084-1086). [/size][/font][/color][size=4] [/size]

[size=4][font=Esprit-Book][font=Esprit-Book]The [font=Esprit-Book][font=Esprit-Book]unique clinical features and the histology (which can be quiet varied) are most consistent with Median Raphe Cyst, as mentioned above [/font][/font][/font][/font][/size]

Median raphe cyst.