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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1003 - 28th April Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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The patient is a 34 year old woman with shave biopsies of a lesion on the left groin.

Case posted by Dr. Mark Hurt.


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Dr. Mona Abdel-Halim

Posted

Dysplastic nevus (moderate/severe dysplasia)

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nick turnbull

Posted

I think it might be Atypical genital or flexural nevi. The associated epidermis is a bit papillomatous. The junctional component quite lintigenous and nested with some architectual atypia. Mild cytological atypia is present also.
Dermal componet looks bland wih maturation, i think. Considering site and age, I guess this is benign

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Robledo F. Rocha

Posted

Nevus of inguinal region comprising enlarged, irregularly shaped and unevenly spaced junctional nests on the flanks of the lesion and intradermal small nests and cords, but inconspicuous junctional component, on the center of the lesion. Cytological features of the melanocytes are bland and mitotic figures were not identified.
I’d call this special site nevus and I’d alert for the likely recurrence of the lesion in a few months due to incomplete excision.

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Dr. Richard Carr

Posted

Looks benign and agree with above but might want to add naevus spilus (agminate naevus) as there may be more than one focus of naevus here.

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Mark A. Hurt MD

Posted

Here are a few more H&E's and Immunos. My response will be later today.

[img]https://dermpathpro.com/uploads/spot_diagnosis_comment_img/CASE1003_Image%2008.jpg[/img]

[img]https://dermpathpro.com/uploads/spot_diagnosis_comment_img/CASE1003_Image%2009.jpg[/img]

[img]https://dermpathpro.com/uploads/spot_diagnosis_comment_img/CASE1003_Image%2010.jpg[/img]

[img]https://dermpathpro.com/uploads/spot_diagnosis_comment_img/CASE1003_Image%2011.jpg[/img]

[img]https://dermpathpro.com/uploads/spot_diagnosis_comment_img/CASE1003_Image%2012.jpg[/img]

[img]https://dermpathpro.com/uploads/spot_diagnosis_comment_img/CASE1003_Image%2013.jpg[/img]


Another Ki-67 (below)[img]https://dermpathpro.com/uploads/spot_diagnosis_comment_img/CASE1003_Image%2014.jpg[/img]

And, still, another ki67 (below)
[img]https://dermpathpro.com/uploads/spot_diagnosis_comment_img/CASE1003_Image%2015.jpg[/img]

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Mark A. Hurt MD

Posted

To Richard's question, there was no clinical indication of nevus spilus.

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Guest Tiberiu Tebeica

Posted

The Ki67 is low in the dermal component. I don't see pagetoid spread. Even though there is some architercural disorder, I think it is related mostly to the anatomical localization. My diagnosis would be special site nevus. It is benign, but I would probably advise the clinician that the lesion might persist / recur with a worrisome look.

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Mark A. Hurt MD

Posted

My diagnosis was superficial congenital melanocytic nevus with balloon cell melanocytes. I have sympathy with flexural nevus and special site nevus.

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