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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1079 - 12th August Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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24 year old male newly diagnosed with HIV. Biopsy of left thigh.

Case posted by Dr.Uma Sundram.
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Go to records August 2014

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Uma Sundram

Uma Sundram 169

Posted

[img]https://dermpathpro.com/uploads/spot_diagnosis_comment_img/CASE1079_SD-US-007-F5.jpg[/img]
Can you all guess the immunohistochemical study and the diagnosis?

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Uma Sundram

Uma Sundram 169

Posted

By the way...the brown wiggles are not melanin.

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Uma Sundram

Uma Sundram 169

Posted

Yes, I called this secondary syphilis. The immunohistochemical stain is a spirochete stain. I hought this was a good example of needing to have a broad differential on light microscopy in newly diagnosed HIV patients since syphilis can mimic a lot of other entities, and can have more interface than granulomatous features.

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