Case Number : Case 1598 - 10 August Posted By: Guest

Pustular lesion is large, but there isn't a psoriasiform hyperplasia neither  spongiform intraepidermal abscess around the big one, so I go with Acute Generalized Exanthematous Pustulosis ( paracetamol? Other? ).

AGEP is a good hypothesis. CPC is needed

Neutrophilic microabscess, with history of sudden onset and 26 year old male

 the DDs are AGEP, Acute exanthematous pustular psoriasis and pustular syphilid

I see probably one area of endothelial swelling in Fig 5 but nt able to appreciate any plasma cells

CPC is required 

Agree with AGEP. There is too much spongiosis for pustular psoriasis althought eosinophils are not clear in these images, another differential diagnosis is Ig A pemphigus that can mimic AGEP. Agree CPC needed

Another differential diagnosis is the rare Amicrobial pustulosis of the folds.

AGEP.  It's hard to see them, but there are eosinophils in the bottom two and the middle right panels.