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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1166- 11th December Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
   (0 reviews)
78 year-old female with cystic mass on right lower lid.

Case posted By Dr. Hafeez Diwan
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  Report Record
Go to records December 2014

User Feedback


Dr. Mona Abdel-Halim

Dr. Mona Abdel-Halim 508

Posted

Agree with apocrine papillary cystadenoma

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Dr. Richard Carr

Dr. Richard Carr 622

Posted

Agree it does not look overtly malignant but with the blue mucin I would also consider a (sparsely) mucinous carcinoma (tubulocystic variant) especially at this anatomic location. The apocrine papillary cystadenoma should have a complete myoepithelial layer on p63.

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Guest Jim Davie MD

Guest Jim Davie MD

Posted

Apocrine papillary cystadenoma, with (eccrine) mucinous metaplasia.

Had seen a similar case before with bland cytology and mixed apocrine/eccrine/mucinous features.
Rare case reports exist, e.g. J Cutan Pathol. 2005 Apr;32(4):307-9.
Eccrine mucinous metaplasia associated with an apocrine cystadenoma. [url="http://www.ncbi.nlm.nih.gov/pubmed/15769281"]http://www.ncbi.nlm.nih.gov/pubmed/15769281[/url]

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Dr. Hafeez Diwan

Dr. Hafeez Diwan 125

Posted

This was signed out as an endocrine mucin producing sweat gland carcinoma of the eyelid. The tumor was synaptophysin positive.

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