Jump to content
In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1178 - 29th December Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
   (0 reviews)

The patient is a 36 year old woman with a shave biopsy of a lesion on the dorsum of the left foot.

Case posted by Dr Mark Hurt


  Report Record

User Feedback


Robledo F. Rocha

Posted

[color=#1C2837][font=arial, verdana, tahoma, sans-serif][size=4]Agree with intradermal desmoplastic nevus once Ki-67 is very low, although I'd feel more comfortable after seeing the whole lesion provided by an excisional biopsy.[/size][/font][/color]

Share this comment


Link to comment
Share on other sites

Guest Jim Davie MD

Posted

Agree with desmoplastic nevus. Minimal Ki67 staining (<1%), and preservation of P16 staining (nuclear and cytoplasmic).

Share this comment


Link to comment
Share on other sites

Dr. Mona Abdel-Halim

Posted

Desmoplastic nevus... It is lovely to c this after the discussion on Friday's case posted by Dr Carr... I owe this website a lot... Thank you all :-)) Wish u all a happy new year...

Share this comment


Link to comment
Share on other sites

Guest Giovanni Falconieri

Posted

This is just a replication of my comment posted early today. [color=#1C2837][font=arial, verdana, tahoma, sans-serif][size=4]Intradermal desmoplastic nevus, if HMB45+ I would go for spitzoid blue nevus (replicate post)[/size][/font][/color]

Share this comment


Link to comment
Share on other sites

Mark A. Hurt MD

Posted

My diagnosis was hypomelanotic blue nevus. As a rule, I don't obtain HMB-45 on these lesions, as Melan-A is usually so strongly positive, S100 (not shown) is generally weakly staining, and Ki67 is negative -- that this trio is highly characteristic of blue nevus, in my experience.

Share this comment


Link to comment
Share on other sites

Dr. Richard Carr

Posted

Nice case Mark. We collected a lot of hypomelanotic S100 weak/negative blue naevi and one or two showed a focally naevocellular area-like pattern as in this case. Like the others I had gone with desmoplastic naevus rather than blue naevus but would certainly accept this as the latter. The site is also very good for blue naevus.

Share this comment


Link to comment
Share on other sites



Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.

Guest
Add a comment...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

Loading...

×
×
  • Create New...