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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1179 - 30th December Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
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75 year-old female with right shin lesion.

Case posted by Dr Hafeez Diwan


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User Feedback


Dr. Mona Abdel-Halim

Posted

? Superficial pleomorphic sarcoma

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Dr. Richard Carr

Posted

Depends on depth and IHC. Atypical dermal smooth muscle tumour / leiomyosarcoma most likely. Quite DF/FH-like epidermal changes though!!

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Guest Giovanni Falconieri

Posted

Agree with the considerations above. I would also add dermal clear cell sarcoma to the differential especially if some melanoma markers turn out to be positive

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Robledo F. Rocha

Posted

Intersecting fascicles of elongated spindle cells with abundant eosinophilic cytoplasm favors a tumor with smooth muscle differentiation. Nuclear pleomorphism and high mitotic activity drive to the diagnosis of leiomyosarcoma.
Happy 2015 to all my dermpath friends!

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Guest Romualdo

Posted

Agree with sarcoma. Probably leiomyosarcoma based on the first two images.

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Mark A. Hurt MD

Posted

Happy new year to all. I agree with the differential. I am concerned about the possibility of melanoma.

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Dr. Hafeez Diwan

Posted

Leiomyosarcoma. Desmin was positive. S-100, Melan-A, CK5/6 were negative.

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