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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 954 - 18th February Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
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The patient is a 62 year old white woman with a shave biopsy of a new, tan papule taken from the right preauricular cheek.

Case posted by Dr. Mark Hurt


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User Feedback


Agree, Epidermolytic acanthoma. It is not surprising that, although different diseases, the histological alterations are similar to the observed in Epidermolytic hyperkeratosis since both have alterations in Keratin 1 and 10.

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Robledo F. Rocha

Posted

Given the case history of a solitary papule of recent onset, I go with epidermolytic acanthoma.

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Mark A. Hurt MD

Posted

My diagnosis was epidermolytic acanthoma. References to follow.

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Mark A. Hurt MD

Posted

1: Kazlouskaya V, Lambe J, Elston D. Solitary epidermolytic acanthoma. J Cutan
Pathol. 2013 Aug;40(8):701-7. doi: 10.1111/cup.12165. Epub 2013 May 24. PubMed
PMID: 23710687.

2: Abbas O, Wieland CN, Goldberg LJ. Solitary epidermolytic acanthoma: a clinical
and histopathological study. J Eur Acad Dermatol Venereol. 2011 Feb;25(2):175-80.
doi: 10.1111/j.1468-3083.2010.03736.x. Epub 2010 Jun 9. Review. PubMed PMID:
20553361.

http://www.ncbi.nlm.nih.gov/pubmed/?term=Epidermolytic+acanthoma

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