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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1043 - 23rd June Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
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The patient is a 34 year old man with an excision taken from the right mid back.

Case posted by Dr. Mark Hurt.


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dermpath1

Posted

Compound nevus with pseudoglandular structures formation.There is pink amorphous material which could
be amylod.In sum compond nevus.

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Robledo F. Rocha

Posted

Compound melanocytic nevus. I've always been very curious about these spaces which appear from time to time within intradermal melanocytic nests, but I’ve never found in the literature a satisfactory explanation for this very intriguing feature. Effect of injection of anesthetic fluid was discarded. Artifact shrinkage during histological processing and loss of the intercellular cohesion are still open hypotheses.

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Dr. Mona Abdel-Halim

Posted

Compound nevus with pseudoglandular changes

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Mark A. Hurt MD

Posted

Here are the immunos:

[img]https://dermpathpro.com/uploads/spot_diagnosis_comment_img/CASE1043_Image%2007.jpg[/img]

[img]https://dermpathpro.com/uploads/spot_diagnosis_comment_img/CASE1043_Image%2008.jpg[/img]

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Mark A. Hurt MD

Posted

My diagnosis was: Superficial congenital melanocytic nevus with pseudo-glands.

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Here are a few relevant references.

1. Burg G, Kempf W, Hochli M, Huwyler T, Panizzon RG. ‘Tubular’ epithelioid cell
nevus: a new variant of Spitz’s nevus. J Cutan Pathol 1998; 25: 475.

2. Soyer HP, Breier F, Cerroni L, Kerl H. ‘Tubular’ structures within
melanocytic proliferations: a distinctive morphologic finding not restricted to
Spitz’s nevi. J Cutan Pathol 1999; 26:315.

3. Ziemer M, Diaz-Cascajo C, Kohler G, Weyers W. Tubular Spitz’s nevus- an
artifact of fixation? J Cutan Pathol 2000; 27:500–504.

4. Requena C, Requena L, Sanchez Yus E. Spitz nevus: a clinicopathological study
of 349 cases. Am J Dermatopathol 2009; 31:107-116.

5. Fujita Y, Tsujiwaki M, Homma E, et al. Tubular Spitz Naevus Mimicking Eccrine
Spiradenoma. Acta Derm Venereol 2014; 94:114–115.

6. Tarlow MM, Nemlick AS, Rothenberg J, Schwartz RA. Pseudoglandular-type
melanoma: a rare melanoma variant. J Cutan Pathol 2008; 35:588–590.

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