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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1044 - 24th June Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
   (0 reviews)
The patient is a 38-year-old white woman with an excision of a pigmented lesion on the nasal tip.

Case posted by Dr. Mark Hurt.
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  Report Record
Go to records June 2014

User Feedback


Eman El-Nabarawy

Eman El-Nabarawy 69

Posted

Amelanotic cellular blue nevus.

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Arti Bakshi

Arti Bakshi 286

Posted

Wedge shaped intradermal melanocytic proliferation with an admixture of spindle and dendritic cells. There is variable pleomorphism, but no mitoses.
Benign, probably a variant of blue naevus.

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nick turnbull

nick turnbull 7

Posted

Agree, hypopigmented blue nevus

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Dr. Mona Abdel-Halim

Dr. Mona Abdel-Halim 508

Posted

Hypopigmented blue nevus

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Robledo F. Rocha

Robledo F. Rocha 336

Posted

My first impression was a benign fibrous tumor, but the presence of a few pigmented cells with bipolar or dendritic processes drove me to the diagnosis of hypopigmented blue nevus.

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Guest Dr Gonzalo de Toro

Guest Dr Gonzalo de Toro

Posted

The lesión is wedge shaped, with some dendritic melanocytes with elongated and neurofibroma-like featues. I favor a hypopigmented blue nevus.

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Dr. Richard Carr

Dr. Richard Carr 622

Posted

Agree with hypopigmented blue naevus. Most of the lesional cells are S100 negative as expected. Nice internal control in Langerhan's cells and nerves.

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Guest Jim Davie MD

Guest Jim Davie MD

Posted

Agree with hypomelanotic blue nevus (possibly congenital).
The bland histology (slightly hyperchromatic senescent nuclei with small to inconspicuous nucleoli), non-expansile architecture (that surrounds and does not significantly disturb/displace arrangement of adnexa), sparse evenly distributed interspersed melanophages, absence of mitotic activity, and absence of inflammatory reaction help support the diagnosis; the immunostains are similarly congruent (no Ki67 or PHH3 detectable proliferative / mitotic activity, and expected positive staining for Melan-A and S100.)

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