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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 965 - 5th March Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
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47 year-old female with papules on forearms, hands and neck. This biopsy is from the forearm.

Case posted by Dr. Hafeez Diwan.
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Go to records March 2014

User Feedback


Robledo F. Rocha

Robledo F. Rocha 336

Posted

Polymorphous light eruption.

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Dr. Richard Carr

Dr. Richard Carr 622

Posted

Purely on the histology my first reaction was cold injury / pernio. I like the suggestion of PLE (but I have very rarely seen that in real life) and I will throw in lupus (tinge of mucin).

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Guest Jim Davie MD

Guest Jim Davie MD

Posted

Agree with Polymorphous light eruption.
Superficial and deep perivascular mononuclear infiltrate with sparse eosinophils, marked pseudo-bullous papillary dermal edema, reactive keratinocyte changes, and a new parakeratotic stratum suggestive of recent, acute onset.
Clinical suggests symmetrical sun-exposed sites. The differential might otherwise include arthropod assault reaction.

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Guest Tiberiu Tebeica

Guest Tiberiu Tebeica

Posted

I also thought initially that this resembles pernio pretty well, but after seeing the clinical description, I favor PMLE.

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Dr. Hafeez Diwan

Dr. Hafeez Diwan 125

Posted

I apologize for the delay. I was having computer problems and couldn't log on earlier. Regarding the diagnosis, I called it PMLE as well.

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