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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 969 - 11th March Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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The patient is a 76 year old white woman with a shave biopsy taken from the right nasolabial fold.

Case posted by Dr. Mark Hurt


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Dr. Mona Abdel-Halim

Posted

Poroma with clear cell changes.

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Dr. Richard Carr

Posted

I agree with mona benign and sweat duct/gland origin. This lesion is quite hard to pigeon hole precisely. I am often descriptive e.g. Apocrine, papillary, hidradenoma.

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Robledo F. Rocha

Posted

Solid-cystic hidradenoma comprised of clear cells and squamoid cells embedded in a sclerotic stroma and continuing with the overlying epidermis.

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Eman El-Nabarawy

Posted

Hidradenoma with connection to the epidermis reminiscent of eccrine poroma.

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'Acrospiroma' should cover the range of possibilities.

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Mark A. Hurt MD

Posted

My diagnosis was apocrine hidradenoma, as this phrase has been used in books with similar examples. Although I must say that the words "apocrine" and "hidradenoma" occurring together seem to be a contradiction in my way of thinking about these lesions. I usually like the combining form "hidr-" to refer to watery secretions produced by a sweat gland. Lesions with apocrine differentiation don't qualify strictly as producing sweat. Thus, papillary apocrine adenoma would be more appropriate in my mind. Of course, historically, terms such as hidradenoma and acrospiroma have been applied to lesions like this one.

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