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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 974 - 18th March Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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The patient is a 35 year old white woman with a punch biopsy taken from the anterior scalp.

Case posted by Dr. Mark Hurt


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Dr. Richard Carr

Posted

Apologies for delay - I have made a detailed post for Friday's case. I am on my holidays and wanted to leave you a bit more time to have a think about it (which is code for I forgot completely).

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Despite the hyperchromasia and hobnailing, my feeling is that this is not an angiosarcoma. Also, I have not come up with an alternative. Maybe an angiofibroma.

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Dr. Mona Abdel-Halim

Posted

My opinion is that these are metastatic adenocarcinoma strands embedded in a sclerotic collagen. Mostly the clinical presentation was scarring alopecia, hence the specimen was transversly cut. Alopecia neoplastica. The spaces are not lined all around with these atypical cells so I did not perceive them as vascular spaces. I think Immunos at the end of the day will solve it. Nice case...

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Dr. Mona Abdel-Halim

Posted

Trichilemmal cyst !!!!!!!

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Eman El-Nabarawy

Posted

So deeper cuts are the best special stain!!! It was the epithelium of the wall of trichilemmal cyst that makes confusion.

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Robledo F. Rocha

Posted

It’s not uncommon the outermost epithelial layer of tricholemmal cysts be found torn out from the remainder of the cyst wall, hence the pseudovascular features of the lesion in the first four pictures.

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