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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 982 - 28th March Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
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F48. Scalp lesion ?benign naevus, ?adnexal tumour

Case posted by Dr. Richard Carr.
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User Feedback


Guest
My first impression was intradermal naevus, but I expect there's more to it; so maybe cellular neurothekeoma or non-neural granular cell tumour.

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Dr. Mona Abdel-Halim

Dr. Mona Abdel-Halim 508

Posted

First impression: cellular neurothekoma.

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Eman El-Nabarawy

Eman El-Nabarawy 69

Posted

Cellular neurothekoma is a poorly circumscribed tumor. I favor non-neural dermal granular cell tumor.

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Dr. Richard Carr

Dr. Richard Carr 622

Posted

Immunostains as follows: CD68++; CD10++ diffuse; Weak focal CD56; S100, MelanA, HMB45, EMA, Mac387, MNF116, Cam5.2 all neg. NKI-C3 diffuse ++ (c/o Dr Eduardo Calonje) & PGP9.5+90%. Hope this helps.

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Dr. Mona Abdel-Halim

Dr. Mona Abdel-Halim 508

Posted

Cellular neurothekoma, first impression confirmed.

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Robledo F. Rocha

Robledo F. Rocha 336

Posted

Superficial intradermal nested epithelioid cells in a hyalinized background favoring cellular neurothekeoma.

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Dr. Richard Carr

Dr. Richard Carr 622

Posted

Well done all. I also favoured cellular neurothekeoma and the case was kindly stained for NKI-C3 by Dr Eduardo Calonje who concurred with the diagnosis. In my experience of other cases a nested pattern resembling naevus can be a clue to the diagnosis in addition to the sclerotic stroma as seen nicely in this case.

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