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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1013 - 12th May Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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The patient is a 57 year old white woman with a punch biopsy taken from the right posterior medial scalp.

Case posted by Dr. Mark Hurt.


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Apocrine papillary cystadenoma with focal mucinous metaplasia.

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Robledo F. Rocha

Posted

[size=4][color=#000000][font=Arial, sans-serif]Solid-cystic apocrine hidrocystoma showing papillae with focal mucinous change that project into cystic lumen and tubular solid areas.[/font][/color][/size]

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Dr. Mona Abdel-Halim

Posted

Apocrine papillary cystadenoma with focal mucinous metaplasia

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Apocrine papillary cystadenoma with focal mucinous metaplasia. the lesion not totaly excised see fig a

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Dr. Richard Carr

Posted

Apocrine tubulopapillary cystadenoma with mucinous metaplasia.

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Guest Jim Davie MD

Posted

Agree. Tubulopapillary hidradenoma. (Too many synonyms for this exist....tubular apocrine adenoma, tubulopapillary apocrine adenoma, papillary tubular adenoma, apocrine cystadenoma, etc. in addition to others, above.) Location on scalp is common.

Well circumscribed nodule with hyaline collagenous, non-inflammatory stroma lacking inflammation, and numerous telangiectatic vessels. Variable glandular, cribriform, cystic, and arborizing papillary architecture. Dual-layer sweat-gland architecture with myoepithelial layer, and cuboidal vs. columnar lumenal cells, some with apocrine snouting. Foamy lumenal cells with goblet-cell features occasionally present, consistent with incidental mucinous metaplasia. No significant cytologic atypia or proliferative activity.

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Mark A. Hurt MD

Posted

My diagnosis was:

[b]-- APOCRINE ADENOMA [/b]
[b]COMMENT:[/b] Some refer to these as tubular apocrine adenomas. Others refer to them as tubulopapillary apocrine adenomas. Still others use the term apocrine cystadenoma.

-----

I agree with all of you -- more or less -- about the diagnosis. Based on what is actually identified in this particular lesion, it is a tubulopapillary apocrine cystadenoma with mucinous metaplasia, as was diagnosed initially by Dr. Abdul-kadir. I resorted to a shorter diagnosis for the report, because I thought it would be less confusing for the clinician.

Thanks for your participation!

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