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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1017 - 16th May Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
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90 years old female.

Case posted by Dr. Richard Carr.
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Go to records May 2014

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Eman El-Nabarawy

Eman El-Nabarawy 69

Posted

Malignant peripheral nerve sheath tumor with probable melanocytic differentiation .

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Guest
Haemosiderotic fibrohistiocytic lipomatous lesion.

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Dr. Mona Abdel-Halim

Dr. Mona Abdel-Halim 508

Posted

I am thinking of hemosiderotic fibrohistiocytic lipomatous tumor, but I am unaware of its possible dermal extension. Can not think in something else. It has to be it!!!! Careful examination of the specimen to exclude possible overlap with myxoinflammatory fibroblastic sarcoma is important since both tumors are interrelated as I have learned from the last Annual Updates in Dermatopathology last April...

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SADAT
Haemosiderotic fibrohistiocytic lipomatous tumor

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Guest Romualdo

Guest Romualdo

Posted

I think the pigment could be melanin and the lesion a melanotic (pigmented) diffuse neurofibroma.

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Guest Jim Davie MD

Guest Jim Davie MD

Posted

Agree with hemosiderotic fibrohistiocytic lipomatous tumor.
Unusual presentation: patient is much older than the common age range (40-70 yrs).
The pigment seems refractile, favoring hemosiderin. Cells show no high grade atypia, conspicuous nucleoli, or proliferative activity. Would expect CD34(+), S100(-) staining pattern.

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dermpath1

dermpath1 3

Posted

Agree with above but Just want to add melanoma and DFSP as a differential.
Snce melaoma is a great mimik, s100 should be done.

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Robledo F. Rocha

Robledo F. Rocha 336

Posted

[font=arial,helvetica,sans-serif][size=4][color=#000000]My first impression is myxoinflammatory fibroblastic sarcoma. Looking for my colleagues' opinion favoring hemosiderotic fibrohistiocytic lipomatous tumor, I discovered both can be related lesions.[/color][/size][/font]

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Dr. Richard Carr

Dr. Richard Carr 622

Posted

I reported this as a haemosiderotic fibrohistiocytic lipomatous lesion / tumour.

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