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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1017 - 16th May Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
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90 years old female.

Case posted by Dr. Richard Carr.


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Eman El-Nabarawy

Posted

Malignant peripheral nerve sheath tumor with probable melanocytic differentiation .

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Haemosiderotic fibrohistiocytic lipomatous lesion.

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Dr. Mona Abdel-Halim

Posted

I am thinking of hemosiderotic fibrohistiocytic lipomatous tumor, but I am unaware of its possible dermal extension. Can not think in something else. It has to be it!!!! Careful examination of the specimen to exclude possible overlap with myxoinflammatory fibroblastic sarcoma is important since both tumors are interrelated as I have learned from the last Annual Updates in Dermatopathology last April...

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Haemosiderotic fibrohistiocytic lipomatous tumor

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Guest Romualdo

Posted

I think the pigment could be melanin and the lesion a melanotic (pigmented) diffuse neurofibroma.

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Guest Jim Davie MD

Posted

Agree with hemosiderotic fibrohistiocytic lipomatous tumor.
Unusual presentation: patient is much older than the common age range (40-70 yrs).
The pigment seems refractile, favoring hemosiderin. Cells show no high grade atypia, conspicuous nucleoli, or proliferative activity. Would expect CD34(+), S100(-) staining pattern.

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dermpath1

Posted

Agree with above but Just want to add melanoma and DFSP as a differential.
Snce melaoma is a great mimik, s100 should be done.

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Robledo F. Rocha

Posted

[font=arial,helvetica,sans-serif][size=4][color=#000000]My first impression is myxoinflammatory fibroblastic sarcoma. Looking for my colleagues' opinion favoring hemosiderotic fibrohistiocytic lipomatous tumor, I discovered both can be related lesions.[/color][/size][/font]

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Dr. Richard Carr

Posted

I reported this as a haemosiderotic fibrohistiocytic lipomatous lesion / tumour.

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Mark A. Hurt MD

Posted

Go to case 1018 fro 19 May 2014 at this link: https://dermpathpro.com/spot-diagnosis-1/_/free-spot-diagnosis-may-2014/may-2014/case-1018-19th-may-r1057

For some reason the home page pointer did not work today.

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