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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1022 - 23rd May Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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M83. Hard lump on glans penis.

Case posted by Dr. Richard Carr.


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Dr. Mona Abdel-Halim

Posted

Penile metastasis of chondrosarcoma.

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?Metastatic chordoma (from sacrococcyx).

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IgorSC

Posted

I agree with the metastasiss of chondrosarcoma. Rare, I heard of a case some years ago with metastasis to the penis.

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Metastatic chordoma:Chordoma may arise from base of skull or from sarcococcygeal area. I think this metastatic chordoma arising from sarcoccygeal region and metaststic chondrosarcoma should be considered as differential diagnosis.

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Robledo F. Rocha

Posted

Agree with metastatic chordoma, probably from primary tumor in the sacrococcygeal region. Round neoplastic cells with abundant clear eosinophilic cytoplasm and central small nuclei. Cells are disposed in cords or in discohesive clusters with some pseudotubular arrangement embedded in a myxoid background.
I'd include cutaneous mixed tumor as a differential diagnosis.

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Dr. Mona Abdel-Halim

Posted

My understanding (which might be wrong) is that cells of chordoma are diffusely foamy, vacuolated or physaliferous cells. I do not think this applies to the cells here. Anyway a keratin stain is needed to verify. Chordomas are keratin positive but chondrosarcomas are not.... Amazing case anyway... Thanks Dr Carr :-))

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Eman El-Nabarawy

Posted

Agree with metastatic chordoma. DD mixed tumor of the skin or myoepithelioma of soft tissue.

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Guest Romualdo

Posted

Metastatic chordoma as first possibility. Metastatic chondrosarcoma and myoepithelioma as differentials.

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Dr. Mona Abdel-Halim

Posted

In addition to the possibility of a metastasis from chondrosarcoma (myxoid chondrosarcoma), (extraskeletal favored actually), I want to add the possibility of primary extraskeletal myxoid chondrosarcoma. Genitourinary tract affection has been reported.


http://journals.sfu.ca/cuaj/index.php/journal/article/download/893/703

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Mark A. Hurt MD

Posted

WOW! I have nothing to add to the differential diagnosis. My best guess from these sections is metastatic chondrosarcoma.

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dermpath1

Posted

Also add [b]Phosphaturic mesenchymal tumor.[/b]

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Dr. Richard Carr

Posted

Wow indeed to Dr Abdul-Kadir. I did not think you would get this one! There was a prior history of a sacrococcygeal chordoma!!!
Enjoy your weekends

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