In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1143 - 10th November Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
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49 year old male. Enlarged nodule, left groin.

Case posted by Dr. Iskander H. Chaudhry


User Feedback


Guest Romualdo

Posted

Intranodal hemorrhagic spindle cell tumor with amianthoid fibers (intranodal palisaded myofibroblastoma).

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Guest Giovanni Falconieri

Posted

Challenging case. With Romualdo input I would also favor nodal myofibroblastoma. Close resemblance to KS has been emphasized by Suster and Rosai in their AJSP seminal paper([url="http://www.ncbi.nlm.nih.gov/pubmed?term=suster%5Bauthor%5D+AND+amianthoid&TransSchema=title&cmd=detailssearch"]http://www.ncbi.nlm....d=detailssearch[/url]).

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Intranodal palisaded myofibroblastoma. The amianthoid fibres are seen on the last image.

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Iskander H. Chaudhry

Posted

[font=arial, sans-serif][size=3]The lesion is HHV8 negative ... any other suggestions[/size][/font]

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Guest Tiberiu Tebeica

Posted

This is absolutely a new one for me :) Thank you so much for sharing and teaching!

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Dr. Mona Abdel-Halim

Posted

So from Dr Iskander's comment, it seems that still the case is undiagnosed !!!!
Another idea crossed my mind just now, what if this is not a lymph node, what if this is angiomatoid fibrous histiocytoma. Thick pseudo capsule, lymphoid follicle aggregates, bland spindle cells , histiocytoid cells and blood filled spaces ...

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Iskander H. Chaudhry

Posted

[font=arial, sans-serif][size=3]The diagnosis is[/size][/font][b] Palisaded myofibroblastoma/intranodal haemorrhagic spindle cell tumour with amianthoid fibres. [/b]

[font=arial, sans-serif][size=3]Well done to all who got this right. [/size][/font]
[font=arial, sans-serif][size=3]
We also wrote a paper on that - Intranodal palisaded myofibroblastoma--an unusual entity. Thiryayi SA, Andrews B, Hall GL, Chaudhry IH. [/size][/font][font=arial, sans-serif][size=3]
[url="http://www.ncbi.nlm.nih.gov/pubmed/21217093"]http://www.ncbi.nlm.nih.gov/pubmed/21217093[/url][/size][/font]

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