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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1154 - 25th November Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
   (0 reviews)

45 year old male with multiple generalized violaceous and erythematous skin lesions.
Otherwise asymptomatic. Biopsy of right arm.

Case posted by Dr.Uma Sundram.


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User Feedback


I see slit-like spaces and vascular and spindle cell proliferation with vacuoles containing red blood cells. Kaposi sarcoma.

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Guest Giovanni Falconieri

Posted

Agree. Kaposi sarcoma. Also distinctive spaces dissecting the collagen bundles, RBC extravasation ... along to a concerning clinical presentation

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Guest Romualdo

Posted

Focally glomeruloid vessels, dermal alterations resembling nodular fasciitis. I think this is cutaneous reactive angiomatosis.

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Agree with Kaposi. It was only yesterday that I saw a case of Kaposi (in a gastric biopsy).

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Guest Tiberiu Tebeica

Posted

My blinded diagnosis was diffuse dermal angiomatosis / reactive angioendotheliomatosis vs. Kaposi's sarcoma. In light of the clinical information, Kaposi's seems more likely. HHV-8 would be helpful.

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Robledo F. Rocha

Posted

In this clinical setting, microscopic images showing proliferation of jagged slit-like vascular spaces that dissect between collagen bundles and protude into a pre-existing vessel as a promontory sign make me think of Kaposi's sarcoma.

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Arti Bakshi

Posted

Agree with Kaposi's sarcoma. Thanks Uma for coming to Manchester and for your fantastic talks today!

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Uma Sundram

Posted

[font=arial, sans-serif][size=3]Kaposi sarcoma. HHV-8 was positive.[/size][/font]

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Mark A. Hurt MD

Posted

Uma, I was happy to see you in Chicago and to catch up. All the best, and thanks for contributing these excellent cases!

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Uma Sundram

Posted

Dear friends, and colleagues in Manchester, Thank you for the opportunity to come to Manchester. The forum was amazing and I had a wonderful time. My thanks to Mark as well for his wonderful mentorship and the opportunity to participate in dermpathpro. It's been an amazing learning experience and you all are really great dermatopathologists! Looking forward to more great cases in 2015.

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