Jump to content
In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1110 - 24th September Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
   (0 reviews)

50 year-old male with vesicular rash. This biopsy is from the right ventral wrist.

Case posted by Dr. Hafeez Diwan.


  Report Record

User Feedback


Guest Tiberiu Tebeica

Posted

dermatitis herpetiformis (most likely) vs. linear IgA bullous dermatosis vs. BP (less likely)

Share this comment


Link to comment
share_externally

Robledo F. Rocha

Posted

An edematous papillary dermis showing neutrophilic microabscesses and reticular network of fibrin made me favor dermatitis herpetiformis. Extensor surface of upper limb is a typical site. Linear IgA disease, its look-alike, is less plausible in a man with his fifties.

Share this comment


Link to comment
share_externally

Dr. Hafeez Diwan

Posted

Immunofluorescence showed this was linear IgA disease.

Share this comment


Link to comment
share_externally

Dr. Richard Carr

Posted

As a general point DH is often hard to diagnose as finding an unexcoriated lesion to biopsy is tricky but histologically we rarely see blistering to the extent seen here so the other suggestions of linear IgA, neutrophil-rich BP and EBA would be more likely. In DH the text-book cases typically have papillary dermal microabscesses limited to a very few dermal papillae and it is one of the (relatively few) indications for close step levels though the entire biopsy.

Share this comment


Link to comment
share_externally



Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.

Guest
Add a comment...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

Loading...

×
×
  • Create New...