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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1253 - 13 April Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
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The patient is a 71-year-old woman with punch biopsies for H&E microscopy and direct immunofluorescence taken from A and B - back.

Case posted by Dr Mark Hurt


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Dr. Mona Abdel-Halim

Posted

Agree, will add SLE as DDx for clinical correlation and serological work up.

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Eman El-Nabarawy

Posted

Dermatomyositis. DD mucinosis of SLE.

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Guest Romualdo

Posted

Agree with the above possibilities. Favor dermatomyositis.

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Mark A. Hurt MD

Posted

My diagnosis:

SKIN, BACK , PUNCH BIOPSY :
[b]-- DERMATOMYOSITIS, consistent with[/b]
[b]COMMENT: [/b]Some lesions of subacute cutaneous lupus and discoid lupus erythematosis can mimic dermatomyositis exactly, so correlation should be done. However, given the clinical diagnosis of dermatomyositis, with these findings and the lack of deposition on direct immunofluorescence, points strongly to dermatomyositis in this case.
SKIN, BACK , PUNCH BIOPSY FOR DIRECT IF :
[b]-- NEGATIVE DIRECT IMMUNOFLUORESCENCE[/b]

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