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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1343 - 17 August Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
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The patient is a 32 year old woman with a shave biopsy of a changing lesion on the left shoulder. Clinical Diagnosis: melanocytic nevus

Case posted by Dr Mark Hurt
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Go to records August 2015

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Arti Bakshi

Arti Bakshi 286

Posted

This lesion has a biphasic appearance with peripheral spindle cells with eosinophilic cytoplasm and central nodular areas with basophilic cells in a myxoid/?chondroid matrx.
?Solitary Myofibroma

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Dr. Mona Abdel-Halim

Dr. Mona Abdel-Halim 508

Posted

Nice suggestion of myofibroma. I did not think of it, I thought of cellular neurothekoma with prominent myxoid stroma. The clinical impression of a melanocytic nevus does not fit with the usual clinical presentation of solitary myofibromas. I am not expert in this area and I am looking forward to the correct diagnosis.

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Arti Bakshi

Arti Bakshi 286

Posted

Very difficult case today! Diffuse S100 obviously points to a neural tumour and rules out the other possibilities considered. But Dr Hurt, isn't the tumour too cellular for a nerve sheath myxoma? Would you consider a variant of dermal schwannoma (plexiform/epithelioid) in the differential ??

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