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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1421- 3 December Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
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Case History: 73 year-old with a mass on superior back.

Case posted by Dr Hafeez Diwan


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User Feedback


Dr. Mona Abdel-Halim

Posted

Plasmacytoma (primary cutaneous vs cutaneous deposits of multiple myeloma).

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Raul Perret

Posted

I would suggest leukemia cutis as a differential

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vincenzo polizzi

Posted

if female, i could thing a metastatic lobular carcinoma of the breast...

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Dr. Mona Abdel-Halim

Posted

Another DDx: cutaneous plasmablastic lymphoma

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Guest Romualdo

Posted

Principally based on the first two images, leukemia is my top choice.

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Arti Bakshi

Posted

Cells have plasmacytoid morphology but are also immature/blastic. Would favour a cutaneous deposit of multiple myeloma. Another differential would be a blastic plasmacytoid dendritic cell neoplasm. Saw a case recently with somewhat similar morphology. Immunos needed.

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binucleation come with MM, and I would do CD117 CD68 , beside the mentioned diagnoses

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Dr. Richard Carr

Posted

Slightly favour lobular carcinoma (think I can see a private acinus) but agree totally with DDx above.

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Dr. Hafeez Diwan

Posted

Metastatic lobular carcinoma of the breast.  The patient has a history of breast carcinoma.  CK7 was positive and E-cadherin was negative.

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