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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1440- 30 December Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
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Case History: 63 year-old male with forearm lesion (biopsied February 2014). Currently, the patient has metastatic lesions in the lung and brain.

Case posted by Dr Hafeez Diwan


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Sasi Attili

Posted

Finding this tricky without immunos. Amelanotic melanoma?

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Guest Romualdo

Posted

One image shows what looks like osteoid. Another possibility is extraskeletal osteogenic sarcoma.

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Nitin Khirwadkar

Posted

Metaplastic amelanotic melanoma. Area with osteoid. Foci that looks angiosarcomatous.

Cutaneous carcinosarcoma will also be in the differential. Difficult without IHC.

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Raul Perret

Posted

Melanoma. Agree on performing a panel of immunos (ck, vim, s-100,desmin, cd31, cd34 and eventually hmb-45, melan A)

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vincenzo polizzi

Posted

Extraskeletal Poorly Differentiated Chondrosarcoma

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Dr. Mona Abdel-Halim

Posted

Immunos are crucial, thinking melanoma and epithelioid angiosarcoma.

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Eman El-Nabarawy

Posted

Favor epithelioid angiosarcoma for immunos.

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Dr. Hafeez Diwan

Posted

Epithelioid angiosaroma with osteoid.  Melanocytic markers were negative.  Positive for CD31, ERG and FLI-1.

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