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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1205 - 04 February Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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37 year-old HIV positive male (CD4 200) with history of Kaposi sarcoma, presenting with numerous perianal hypopigmented papules and plaques.

Case posted by Dr Hafeez Diwan


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Guest Romualdo

Posted

I think this is bowenoid papulosis, but the information that the papules and plaques are "hypopigmented" confused me.

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Dr. Mona Abdel-Halim

Posted

Due to the clinical presentation with hypopigmented lesions, I prefer to call it anal intraepithelial neoplasia.

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Guest Jim Davie MD

Posted

Agree with Bowenoid papulosis, in context of discrete perianal papules. Low-grade random atypia/enlargement in stratum spinosum keratinocytes, koilocytic changes (aberrant molded multinucleation or perinuclear clearing), sparse high level mitoses and sparse apoptosis, and scattered microscopic mounds of "paradoxical parakeratosis" overlying hypergranulosis (1st image).

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Guest Tiberiu Tebeica

Posted

Is there any difference in the clinical approach for bowenoid papulosis vs. AIN?

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