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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1181 - 1st January 2015 Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
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45 year old woman with solitary erythematous nodule on right forearm.

Case posted by Dr Uma Sundram


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Dr. Mona Abdel-Halim

Posted

I expect CD30 was positive. Anaplastic large T cell lymphoma.

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Eman El-Nabarawy

Posted

Anaplastic large T cell lymphoma.

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Uma Sundram

Posted

[img]https://dermpathpro.com/uploads/spot_diagnosis_comment_img/Case%201181%20-%20SD_US-027-F5.jpg[/img]

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Uma Sundram

Posted

Absolutely correct. Primary cutaneous anaplastic large cell lymphoma, determined after a complete clinical workup to exclude systemic ALCL. The immunostain posted is CD30, blazingly positive with focal Golgi staining. Happy New Year, everyone!!

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Uma Sundram

Posted

A post script to this case: The patient never had waxing and waning papules, and this lesion was a nodule that did not regress. This history is important to solicit as these findings are identical to those seen in lesions of type C lymphomatoid papulosis. A non regressing solitary nodule is more typical of anaplastic large cell lymphoma.

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