Jump to content
In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1318 - 13 July Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
   (0 reviews)

The patient is a 38-year-old woman with a biopsy of a lesion on the scalp.

Case posted by Dr Mark Hurt


  Report Record

User Feedback


Eman El-Nabarawy

Posted

Verrucous trichilemmal cyst with epithelial proliferation. I will ask for serial sections to verify possible dysplastic changes.

Share this comment


Link to comment
Share on other sites

Guest Romualdo

Posted

Squamous cell carcinoma arising in a proliferating pilar (trichilemmal) cyst.

Share this comment


Link to comment
Share on other sites

Proliferating trichilemmal tumor.

Share this comment


Link to comment
Share on other sites

Mark A. Hurt MD

Posted

Here's my diagnosis:

[b]-- PROLIFERATIVE TRICHOLEMMAL CYSTIC CARCINOMA[/b]
[indent=1][b]COMMENT:[/b] The differential diagnosis is with proliferative tricholemmal cystic acanthoma, the benign analog to this lesion. Some use the term proliferative tricholemmal cyst to refer to these types of lesions, but I think that designation really doesn't capture the broad spectrum of changes that can occur in these lesions. Most of them tend to act like low grade carcinomas, but some of them have been more aggressive and published in the literature (see references below). In any event, I don't see any evidence of the lesion involving the margins of resection, and adipose tissue is identified deep.[/indent]


[indent=1]1. Sau P, Graham JH, Helwig EB. Proliferating epithelial cysts. Clinicopathological analysis of 96 cases. J Cutan Pathol. 1995 Oct;22(5):394-406. PubMed PMID: 8594071.[/indent]

[indent=1]2. Ackerman AB, Mones JM. Proliferating tricholemmal cystic carcinoma (Revision of chapter XXV of the volume titled Neoplasms with Follicular Differentiation, 2nd edition by Ackerman, Reddy, and Soyer, Ardor Scribendi, Ltd., 2001). In: Dermatopathol Pract Concept 2006; 12:2.[/indent]

Share this comment


Link to comment
Share on other sites



Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.

Guest
Add a comment...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

Loading...

×
×
  • Create New...