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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1325 - 22 July Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
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1 year-old male with arm lesion.

Case posted by Dr Hafeez Diwan


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Dr. Mona Abdel-Halim

Posted

Thinking of infantile desmoid like fibromatosis ?
Although site, sex and age is typical of fibrous hamartoma of infancy, the histology does not show the typical fasicular arrangement of myofibroblastic cells or the whorls of myxoid foci with undifferentiated cells.
Would love to see other opinions.

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Dr. Richard Carr

Posted

Arti thinks it might be myofibromatosis (she is visiting with me!)

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Eman El-Nabarawy

Posted

I thought of monophasic myofibroma.

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Guest Romualdo

Posted

According to the WHO book this is lipofibromatosis. Although some authors also call this lesion infantile fibromatosis, lipofibromatosis is a prefered term, since it takes into account the mature adipose tissue that is always present. The presence of adipose tissue is the principal difference between lipofibromatosis and desmoid type fibromatosis. The absence of foci of small, round to spindled, imature cells distinguishes lipofibromatosis from fibrous hamartoma of infancy, as Mona emphasized.

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Dr. Mona Abdel-Halim

Posted

http://www.ncbi.nlm.nih.gov/m/pubmed/11075850/

I think Romualdo got it right, lipofibromatosis it is :-)

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Dr. Hafeez Diwan

Posted

Fibrous hamartoma of infancy vs. lipofibromatosis - good discussion! This is actually a re-excision. It had been previously biopsied and then re-excised.

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