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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1291 - 04 June Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
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67 year-old with biopsy from left back.

Case posted by Dr Hafeez Diwan
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  Report Record
Go to records June 2015

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Guest Romualdo

Guest Romualdo

Posted

What is the patient's sex?

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Arti Bakshi

Arti Bakshi 286

Posted

There appears to be an 'Indian file' pattern of infiltration by tumour cells. First thought is metastatic lobular Ca of Breast (presumably that is the reason for Romualdo' question!), Will need immunos however to exclude lymphoma/leukaemia/merkel cell etc.

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Hanan Vaknine MD

Hanan Vaknine MD 18

Posted

The emphasis on the well preserved Grenz zone and the immunoblastic and plasmablastic character of the cells, together with the absence of accompanying small lymphocytes are suggestive of DLBCL-leg type, however in figures 5&6 the cells appear somewhat cohesive (metastatic carcinoma?). The prominent nucleoli and the vesicular chromatin is less convening of Merkel cell carcinoma in my opinion, but I am keeping an open mind.

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Dr. Mona Abdel-Halim

Dr. Mona Abdel-Halim 508

Posted

Lymphoma (DLBCL) vs. metastatic carcinoma

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Dr. Hafeez Diwan

Dr. Hafeez Diwan 125

Posted

Male patient. Leukemia cutis. THe patient had leukemia.

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Dr. Hafeez Diwan

Dr. Hafeez Diwan 125

Posted

I have posted yesterday's diagnosis as well.

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Guest Romualdo

Guest Romualdo

Posted

My first thought is granulocytic sarcoma , followed by metastatic breast carcinoma, if the patient is a female.

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