Case Number : Case 1293 - 08 June Posted By: Guest

Cutaneous adenoid cystic carcinoma.

I think there are decapitation secretion, too much atypia and papillary foci. I think this is apocrine carcinoma.

Agree with apocrine carcinoma.

[b]-- CRIBRIFORM APOCRINE ADENOCARCINOMA[/b]
[indent=1][b]COMMENT: [/b]This is a low grade adnexal adenocarcinoma of the skin, and the reported patients have done fairly well in 13 of 26 patients follow-up by Rütten et al in 2009; none of the lesions were known to have metastasized or regrow locally. There was a question about this being a ductal adenoma or mixed tumor, and I don't think it qualifies for either. As a rule mixed tumors will have less of a cribriform pattern and usually have different elements such as peculiar stroma or even cartilaginous stroma and adipose tissue. As a rule the ductal adenomas don't make this stereotyped pattern. Cribriform apocrine carcinoma is an uncommonly found lesion, and it appears to be low grade, but I still think it needs to be excised.[/indent]

[center]Reference[/center]

Rütten A, Kutzner H, Mentzel T, Hantschke M, Eckert F, Angulo J, Rodríguez Peralto JL, Requena L. Primary cutaneous cribriform apocrine carcinoma: a clinicopathologic and immunohistochemical study of 26 cases of an under-recognized cutaneous adnexal neoplasm. J Am Acad Dermatol. 2009 Oct;61(4):644-51. doi: 10.1016/j.jaad.2009.03.032. PubMed PMID: 19751882.