Case Number : Case 1230 - 11 March Posted By: Guest

Epidermal naevus vs condyloma acuminata.

Heck's disease?

No parakeratosis, irregular acanthosis, anastmosing rete ridges, koilocytes and ??mitosoid bodies in figure

4 (one at lower part and one at the right side)---Heck's disease

I also think this is Heck's disease (focal epithelial hyperplasia) and was desperately looking for a mitosoid body, although I'm not sure I can spot a convincing one.

Very nice case..
As AbdulKadir, I thought of viral wart (condyloma accuminatum) but after reading about Heck's disease, I think this is the better term for this case, given the Hispanic origin which is predominately affected. It is a HPV induced epithelial hyperplasia caused by specific types of HPV other than those causing condylomas (according to McKee's pathology of skin, condylomas do not contain HPV 13, 32, found in Heck's disease) Condyloma accuminatum is the clinical and histopathological differential diagnosis....
I am not sure I can c a mitosoid figure :-((
Thank you Romualdo, Biswanath and Tiberiu for letting us revise an entity read few years ago but was forgotten :-))

Broad anastomosing rete ridges points to Heck's disease.

Great discussion! Yes, this Heck's disease.