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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1231 - 12 March Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
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31 year-old Hispanic female with rash. This biopsy is from the left elbow.

Case posted by Dr Hafeez Diwan


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User Feedback


I see subtle basal vacuolization and melanin incontinence. I'm unsure if picture 6 is showing mucin. If that's the case and given that the biopsy is from the elbow, I'm wondering about dermatomyositis. A clinical description of the rash would be helpful.

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Dr. Mona Abdel-Halim

Posted

Agree with Abdul-Kadir..

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Guest Jim Davie MD

Posted

Agree with dermatomyositis, with differential of lupus. Agree with mucin in picture 6, with rare necrotic keratinocytes and vacuolar change at the DE junction, hyperkeratosis. Rather sparse perivascular chronic infiltrate with no adnexal involvement.

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biswanath behera

Posted

Agree with Dermatomyositis.


what about Subcutaneous lupus erythemosus- Psoriasiform type

i feel. in Figure 4, 3 lymphocytes look indented, some degree of vascular proliferation in uuper dermis in Figue 3 and dilated lymphatics in Figure 7 . any significance of these findings?????

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Dr. Hafeez Diwan

Posted

Dermatomyositis, which was the clinical impression as well.

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