Jump to content
In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1417- 27 November Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
   (0 reviews)
Case History: "M55. No drugs. Sub-erythrodermic rash with areas of sparing, 3/52 rash sun-exposed site ?subacute lupus erythematous, ?eczema, ?drug reaction.

Case posted by Dr Richard Carr
picture-1
picture-2
picture-3
picture-4
  Report Record
Go to records November 2015

User Feedback


Dr. Mona Abdel-Halim

Dr. Mona Abdel-Halim 508

Posted

Diffuse orthokeratosis with spotty parakeratosis with a hint of alternation vertically and horizontally, peri nuclear vacuolization, areas of hypergranulosis, together with the clinical description of sub erythroderma with areas of sparing, I am thinking of PRP. I think the clefting is incidental.

Share this comment

Link to comment
share_externally
Dr. Mona Abdel-Halim

Dr. Mona Abdel-Halim 508

Posted

Another thought as regards the clefting: the cleft looks like that of superficial pemphigus except that there is no frank acantholytic cells. I have found this article:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505938/#!po=27.7778
Could it be a similar case?

Share this comment

Link to comment
share_externally
Guest
The cornified layer is focally parakeratotic, the granular layer is present and the epidermis is psoriasiform. I agree with pityriasis rubra pilaris.

Share this comment

Link to comment
share_externally
Arti Bakshi

Arti Bakshi 286

Posted

Yes, PRP, both clinically and histologically. (agree with Mona that the clefting looks artefactual)
This case looks familiar!!!

Share this comment

Link to comment
share_externally
Dr. Richard Carr

Dr. Richard Carr 622

Posted

Initially I wondered if this was psoriasis (becasue of fairly prominent acanthosis and fairly conflutent parakeratosis) but we reviewed the case with clinical images and we concluded PRP.  I thought the rather rounded profile to the rete ridges was well seen in this case.  Well done Mona again! I interepreted the cleft as artefact but thanks for the helpful additional discussion.

Share this comment

Link to comment
share_externally


Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.

Guest
Add a comment...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

Loading...
×

×
×
  • Create New...