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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1361 - 10 September Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
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19 year old with mass lateral side of nose.


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Dr. Mona Abdel-Halim

Posted

I think we r having an atypical plasma cell priferation. I think ? Dutcher bodies (intranuclear includions) r seen in the third image. Thinking of extramedullary plasmacytoma.

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Arti Bakshi

Posted

Needs a wide panel of immunos. Given the site and focal angiocentric pattern, could be an an extra nodal NK/T cell lymphoma. Other than lymphoid markers, would also do desmin, myogenin etc to rule out embryonal rhabdomyosarcoma.

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Guest Romualdo

Posted

Agregates of discoheseve neoplastic cells separated by fibrovascular septa. Neoplastic cells frequently with excentric atypical nuclei and cytoplasmic eosinophilic inclusions. These findings are highly suggestive of alveolar rhabdomyosarcoma, solid variant, to IHC confirmation.

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Dr. Mona Abdel-Halim

Posted

Looking again to the images after reading Arti's and Romualdo's comments, I think the correct diagnosis is alveolar rhabdomyosarcoma as they have suggested.

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Dr. Richard Carr

Posted

Difficult. Crush artefact usually a pointer to the delicate cells of a lymphoma but I need IHC! NK/T-cell top of the list.

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Iskander H. Chaudhry

Posted

Thank you for the comments and as you say we would do a wide range of immuno', after which the final diagnosis was: Embryonal Rhabdomyosarcoma

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