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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1508 - 05 April Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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45 year old woman with lesion on abdomen.

Dr Uma Sundram.


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vincenzo polizzi

Posted

Compound Nevus, dysplastic type.

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vincenzo polizzi

Posted

I have recently known this entity in this site, it was a nested in situ melanoma ( P.McKee ), but in this case it would be a nested invasive melanoma...I've never diagnosed this entity before...So i will try to learn something about...

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vincenzo polizzi

Posted

The patient isn't an elderly person, and the lesions site isn't a solar exposed one. I see only subtle atypia ( no nuclear membrane chromatin accentuation, no nucleola )...

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Dr. Mona Abdel-Halim

Posted

I favour also nested melanoma

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Raul Perret

Posted

Agree with nested melanoma as Kutzner et al. proposed. There is a Borst Jadassohn like phenomenon, we had a similar case recently.

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Dr. Richard Carr

Posted

Based on the information provided and histology we have to say thin atypical melanocytic proliferation uncertain for malignancy (i.e. a MELTUMP). To quote the paper cited by Raul "...consider ancillary tests such as aCGH to confirm the diagnosis in difficult cases. Close communication with the clinician and correlation of the clinical, dermatoscopic, and pathological findings is critical to ensure accurate diagnosis."

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Uma Sundram

Posted

Sorry for the delay in posting, the website was down. Yes, we too were concerned about this lesion and made a diagnosis similar to Dr. Carr, i.e., atypical compound melanocytic proliferation. We asked that the lesion be completely excised (narrow rim of normal skin). Analysis via aCGH did not support the diagnosis of melanoma.

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