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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1519 - 20 April Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
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39 year-old male with biopsy from unspecified site for evaluation of bullous disease

Dr Hafeez Diwan.


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Raul Perret

Posted

Pemphigus probably foliaceous or IgA associated. Favour the first one due to paucity of neutrophils but with pemphigus anything can happen... The Young age of the patient is particular

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Dr. Mona Abdel-Halim

Posted

Superficial pemphigus

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Raul Perret

Posted

Forgot to add P herpetiformis but of course without clinical info a dx of superficial pemphigus should be rendered as Mona suggests

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vincenzo polizzi

Posted

Favor IgA Pemphigus because of neutrophilic infiltrate. There is a regenerate epidermis over the bullous damage... 

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Arti Bakshi

Posted

superficial pemphigus, most likely P.foliaceous

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Pemphigus.  I'm unsure what the last pictures is supposed to show. 

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Dr. Hafeez Diwan

Posted

The last picture (bottom right) shows an eosinophil.  The top two panels are IgG.  There was also some C3 in the lower portion of the epidermis, but it didn't photograph well and I didn't include it.  Pemphigus foliaceus.

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