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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1521 - 22 April Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
   (0 reviews)
M60. Lesion right knee, 6-7 years. Recent episode of bleeding. ?Angioma


Dr Richard Carr.
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Go to records April 2016

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vincenzo polizzi

vincenzo polizzi 185

Posted

Epithelioid dermatofibroma. Nice epidermal collarette.

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Dr. Mona Abdel-Halim

Dr. Mona Abdel-Halim 508

Posted

Perineurioma first thought. Agree with epithelioid fibrous histiocytoma as a ddx

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vincenzo polizzi

vincenzo polizzi 185

Posted

I favor ED aka epithelioid cell histiocytoma, because fits better on CPC. It is a red polypoid nodule ( clinically angioma ) and shows ectatic vessels in keeping With recent bleeding. Histologically looks like more cellular that epithelioid but this is in keeping with Epithelioid Dermatofibroma.

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Nitin Khirwadkar

Nitin Khirwadkar 63

Posted

Agree with the differentials.

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Guest Arash Daryakarr

Guest Arash Daryakarr

Posted

I favor epithelioid fibrous histiocytoma due to clinical presentation (usually presents as a red nodule which usually confused with pyogenic granuloma) and histomorphologic charactristics.
Distinction from epithelioid perineurioma can be made by IHC for EMA and claudin-1.

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Arti Bakshi

Arti Bakshi 286

Posted

Yes, epithelioid fibrous histiocytoma vs perineurioma

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Dr. Mona Abdel-Halim

Dr. Mona Abdel-Halim 508

Posted

So it is perineurioma :-)

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Dr. Richard Carr

Dr. Richard Carr 622

Posted

Good discussion. I reported it as a perineurioma.

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