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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1521 - 22 April Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
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M60. Lesion right knee, 6-7 years. Recent episode of bleeding. ?Angioma


Dr Richard Carr.


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vincenzo polizzi

Posted

Epithelioid dermatofibroma. Nice epidermal collarette.

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I'll add perineurioma as a differential. 

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Dr. Mona Abdel-Halim

Posted

Perineurioma first thought. Agree with epithelioid fibrous histiocytoma as a ddx

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vincenzo polizzi

Posted

I favor ED aka epithelioid cell histiocytoma, because fits better on CPC. It is a red polypoid nodule ( clinically angioma ) and shows ectatic vessels in keeping With recent bleeding. Histologically looks like more cellular that epithelioid but this is in keeping with Epithelioid Dermatofibroma.

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Nitin Khirwadkar

Posted

Agree with the differentials.

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Guest Arash Daryakarr

Posted

I favor epithelioid fibrous histiocytoma due to clinical presentation (usually presents as a red nodule which usually confused with pyogenic granuloma) and histomorphologic charactristics.
Distinction from epithelioid perineurioma can be made by IHC for EMA and claudin-1.

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Arti Bakshi

Posted

Yes, epithelioid fibrous histiocytoma vs perineurioma

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Dr. Mona Abdel-Halim

Posted

So it is perineurioma :-)

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Dr. Richard Carr

Posted

Good discussion. I reported it as a perineurioma.

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