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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1598 - 10 August Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
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26 year-old female with acute onset rash with pustules.

Case posted by Hafeez Diwan


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vincenzo polizzi

Posted

Pustular lesion is large, but there isn't a psoriasiform hyperplasia neither  spongiform intraepidermal abscess around the big one, so I go with Acute Generalized Exanthematous Pustulosis ( paracetamol? Other? ).

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AGEP is a good hypothesis. CPC is needed

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biswanath behera

Posted

Neutrophilic microabscess, with history of sudden onset and 26 year old male

 

 the DDs are AGEP, Acute exanthematous pustular psoriasis and pustular syphilid

 

I see probably one area of endothelial swelling in Fig 5 but nt able to appreciate any plasma cells

 

CPC is required 

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Raul Perret

Posted

Agree with AGEP. There is too much spongiosis for pustular psoriasis althought eosinophils are not clear in these images, another differential diagnosis is Ig A pemphigus that can mimic AGEP. Agree CPC needed

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Another differential diagnosis is the rare Amicrobial pustulosis of the folds.

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Dr. Hafeez Diwan

Posted

AGEP.  It's hard to see them, but there are eosinophils in the bottom two and the middle right panels.

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